Synucleinopathy-associated pathogenesis in Parkinson’s disease and the potential for brain-derived neurotrophic factor

Abstract The lack of disease-modifying treatments for Parkinson’s disease (PD) is in part due to an incomplete understanding of the disease’s etiology. Alpha-synuclein (α-syn) has become a point of focus in PD due to its connection to both familial and idiopathic cases—specifically its localization...

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Bibliographic Details
Main Authors: Kathryn M. Miller, Natosha M. Mercado, Caryl E. Sortwell
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00179-6