Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer’s disease

Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer’s disease

Summary: Alzheimer’s disease (AD) is associated with both extracellular amyloid-β (Aβ) plaques and intracellular tau-containing neurofibrillary tangles (NFT). We characterized the behavioral, metabolic and lipidomic phenotype of the 5xFADxTg30 mouse model which contains overexpression of both Aβ and...

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Bibliographic Details
Main Authors: J.P.S. Marshall, K. Huynh, G.I. Lancaster, J. Ng, J.M. Collins, G. Pernes, A. Liang, T. Featherby, N.A. Mellet, B.G. Drew, A.C. Calkin, A.E. King, P.J. Meikle, M.A. Febbraio, P.A. Adlard, D.C. Henstridge
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Animal physiology
Neuroscience
Behavioral neuroscience
Lipidomics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422400021X

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http://www.sciencedirect.com/science/article/pii/S258900422400021X

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