Posterior inference of Hi-C contact frequency through sampling
Hi-C is one of the most widely used approaches to study three-dimensional genome conformations. Contacts captured by a Hi-C experiment are represented in a contact frequency matrix. Due to the limited sequencing depth and other factors, Hi-C contact frequency matrices are only approximations of the...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-02-01
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Series: | Frontiers in Bioinformatics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbinf.2023.1285828/full |