Posterior inference of Hi-C contact frequency through sampling

Hi-C is one of the most widely used approaches to study three-dimensional genome conformations. Contacts captured by a Hi-C experiment are represented in a contact frequency matrix. Due to the limited sequencing depth and other factors, Hi-C contact frequency matrices are only approximations of the...

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Bibliographic Details
Main Authors: Yanlin Zhang, Christopher J. F. Cameron, Mathieu Blanchette
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Bioinformatics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2023.1285828/full