SARS-CoV-2 primed platelets–derived microRNAs enhance NETs formation by extracellular vesicle transmission and TLR7/8 activation

SARS-CoV-2 primed platelets–derived microRNAs enhance NETs formation by extracellular vesicle transmission and TLR7/8 activation

Abstract Background Hyperactive neutrophil extracellular traps (NETs) formation plays a key role in the pathogenesis of severe COVID-19. Extracellular vesicles (EVs) are vehicles which carry cellular components for intercellular communication. The association between COVID-19 patients-derived EVs an...

Full description

Bibliographic Details
Main Authors: Tsai-Ling Liao, Hung-Jen Liu, Der-Yuan Chen, Kuo-Tung Tang, Yi-Ming Chen, Po-Yu Liu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
COVID-19
extracellular vesicles
Platelets, NETs
microRNAs
TLR8
Online Access:https://doi.org/10.1186/s12964-023-01345-4

Internet

https://doi.org/10.1186/s12964-023-01345-4

Similar Items