Establishment of a Human Immunocompetent 3D Tissue Model to Enable the Long-Term Examination of Biofilm–Tissue Interactions

Establishment of a Human Immunocompetent 3D Tissue Model to Enable the Long-Term Examination of Biofilm–Tissue Interactions

Different studies suggest an impact of biofilms on carcinogenic lesion formation in varying human tissues. However, the mechanisms of cancer formation are difficult to examine in vivo as well as in vitro. Cell culture approaches, in most cases, are unable to keep a bacterial steady state without any...

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Bibliographic Details
Main Authors: Rasika Murkar, Charlotte von Heckel, Heike Walles, Theresia Barbara Moch, Christoph Arens, Nikolaos Davaris, André Weber, Werner Zuschratter, Sönke Baumann, Jörg Reinhardt, Sascha Kopp
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Bioengineering
Subjects:
human 3D tissue model
biofilm
immunocompetent
macrophages
tissue engineering
primary cells
Online Access:https://www.mdpi.com/2306-5354/11/2/187

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https://www.mdpi.com/2306-5354/11/2/187

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