Prediction of ACE-I Inhibitory Peptides Derived from Chickpea (<i>Cicer arietinum</i> L.): In Silico Assessments Using Simulated Enzymatic Hydrolysis, Molecular Docking and ADMET Evaluation

Prediction of ACE-I Inhibitory Peptides Derived from Chickpea (<i>Cicer arietinum</i> L.): In Silico Assessments Using Simulated Enzymatic Hydrolysis, Molecular Docking and ADMET Evaluation

Chickpea (<i>Cicer arietinum</i> L.) peptides have shown in vitro potential to inhibit the angiotensin I-converting enzyme (ACE-I). However, the potential molecular interactions between chickpea peptides (CP) and ACE-I as well as their ADMET (absorption/distribution/metabolism/excretion/...

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Bibliographic Details
Main Authors: Jesús Gilberto Arámburo-Gálvez, Aldo Alejandro Arvizu-Flores, Feliznando Isidro Cárdenas-Torres, Francisco Cabrera-Chávez, Giovanni I. Ramírez-Torres, Lilian Karem Flores-Mendoza, Pedro Erick Gastelum-Acosta, Oscar Gerardo Figueroa-Salcido, Noé Ontiveros
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Foods
Subjects:
ACE-I
antihypertensive peptides
hypertension
bioactive peptides
chickpea
molecular docking
Online Access:https://www.mdpi.com/2304-8158/11/11/1576

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https://www.mdpi.com/2304-8158/11/11/1576

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