Inhibition of Pyruvate Kinase From Thermoanaerobacterium saccharolyticum by IMP Is Independent of the Extra-C Domain

Inhibition of Pyruvate Kinase From Thermoanaerobacterium saccharolyticum by IMP Is Independent of the Extra-C Domain

The pyruvate kinase (PYK) isozyme from Thermoanaerobacterium saccharolyticum (TsPYK) has previously been used in metabolic engineering for improved ethanol production. This isozyme belongs to a subclass of PYK isozymes that include an extra C-domain. Like other isozymes that include this extra C-dom...

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Bibliographic Details
Main Authors: Christopher A. Fenton, Qingling Tang, Daniel G. Olson, Marybeth I. Maloney, Jeffrey L. Bose, Lee R. Lynd, Aron W. Fenton
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Microbiology
Subjects:
allosteric regulation
allostery
pyruvate kinase
ethanol
metabolic engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.628308/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.628308/full

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