Fundamental Concepts in the Assessment of Interaction of Biological Response Modifiers with other Agents
The universal response surface approach (URSA) was developed to assess the nature and intensity of drug interactions, ie, synergism. antagonism and additivity. URSA consists of fitting a concentration-effect surface to experimental data with maximum likelihood approaches, with the estimation of para...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
1992-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1992/895087 |