Gallic acid induces T-helper-1-like Treg cells and strengthens immune checkpoint blockade efficacy

Gallic acid induces T-helper-1-like Treg cells and strengthens immune checkpoint blockade efficacy

Background Foxp3+ regulatory T (Treg) cells facilitate tumor immune evasion by forming a suppressive tumor microenvironment. Therefore, immune therapies promoting Treg fragility may greatly enhance immune checkpoint blockade (ICB) efficacy in cancers.Methods We have screened 2640 compounds and ident...

Full description

Bibliographic Details
Main Authors: Bin Li, Yangyang Li, Yongjun Dang, Biaolong Deng, Biaolong Yang, Jieqiong Chen, Shuaiwei Wang, Weiqi Zhang, Yixian Guo, Yichao Han, Hecheng Li, Yaqin Yuan, Xueyu Dai, Yuansheng Zang
Format: Article
Language:English
Published: BMJ Publishing Group 2022-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/7/e004037.full

Internet

https://jitc.bmj.com/content/10/7/e004037.full

Similar Items