Kinin B2 Receptor Activation Prevents the Evolution of Alzheimer’s Disease Pathological Characteristics in a Transgenic Mouse Model

Kinin B2 Receptor Activation Prevents the Evolution of Alzheimer’s Disease Pathological Characteristics in a Transgenic Mouse Model

Background: Alzheimer’s disease is mainly characterized by remarkable neurodegeneration in brain areas related to memory formation. This progressive neurodegeneration causes cognitive impairment, changes in behavior, functional disability, and even death. Our group has demonstrated changes in the ka...

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Bibliographic Details
Main Authors: Marielza Andrade Nunes, Mariana Toricelli, Natalia Mendes Schöwe, Helena Nascimento Malerba, Karis Ester Dong-Creste, Daniela Moura Azevedo Tuma Farah, Katia De Angelis, Maria Claudia Irigoyen, Fernand Gobeil, Tânia Araujo Viel, Hudson Sousa Buck
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceuticals
Subjects:
Alzheimer’s disease
bradykinin
neurodegenerative diseases
B2 receptor
kallikrein–kinin system
Online Access:https://www.mdpi.com/1424-8247/13/10/288

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https://www.mdpi.com/1424-8247/13/10/288

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