Potential Fluorescent Ligands for Zn-Containing Bacterial Enzymes: In Silico Evaluation, Synthesis and Optical Properties

Potential Fluorescent Ligands for Zn-Containing Bacterial Enzymes: In Silico Evaluation, Synthesis and Optical Properties

Zn-containing proteins play essential roles in the viability and virulence of bacteria, so are considered to be possible molecular new drug targets. Based on literature data about <i>N</i>-acyl-o-phenylenediamine and 2-pycolylamine as warheads of drugs and molecular probes for Zn-bearing...

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Bibliographic Details
Main Authors: Viktoryia Zavalinich, Liliya Glinskaya, Polina Yakovets, Yaroslav Faletrov, Vladimir Shkumatov
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Chemistry Proceedings
Subjects:
fluorescent compounds
zinc containing enzymes
DFT
ciprofloxacin
ortho-phenylenediamine
7-nitrobenzoxadiazole-chloride
Online Access:https://www.mdpi.com/2673-4583/12/1/82

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https://www.mdpi.com/2673-4583/12/1/82

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