The nuclear receptor ERR cooperates with the cardiogenic factor GATA4 to orchestrate cardiomyocyte maturation

The nuclear receptor ERR cooperates with the cardiogenic factor GATA4 to orchestrate cardiomyocyte maturation

Mature cardiac muscle requires high mitochondrial ATP production and specialized contractile proteins. Here the authors demonstrate that cardiomyocyte-specific contractile maturation involves cooperation between the nuclear receptor ERRγ and cardiogenic transcription factor GATA4, but ERRγ controls...

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Bibliographic Details
Main Authors: Tomoya Sakamoto, Kirill Batmanov, Shibiao Wan, Yuanjun Guo, Ling Lai, Rick B. Vega, Daniel P. Kelly
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29733-3

Internet

https://doi.org/10.1038/s41467-022-29733-3

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