Enhanced Epithelial-to-Mesenchymal Transition and Chemoresistance in Advanced Retinoblastoma Tumors Is Driven by miR-181a

Enhanced Epithelial-to-Mesenchymal Transition and Chemoresistance in Advanced Retinoblastoma Tumors Is Driven by miR-181a

Advanced retinoblastoma (Rb) tumors display high metastatic spread to distant tissues, causing a potent threat to vision and life. Through transcriptomic profiling, we discovered key upregulated genes that belonged to the epithelial–mesenchymal transition (EMT) and chemotherapy resistance pathways i...

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Bibliographic Details
Main Authors: Vishnu Suresh Babu, Anadi Bisht, Ashwin Mallipatna, Deepak SA, Gagan Dudeja, Ramaraj Kannan, Rohit Shetty, Nilanjan Guha, Stephane Heymans, Arkasubhra Ghosh
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
EMT
miRNA
retinoblastoma
chemo-resistant
Online Access:https://www.mdpi.com/2072-6694/14/20/5124

Internet

https://www.mdpi.com/2072-6694/14/20/5124

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