TWEAK/Fn14 and non-canonical NF-kappaB signaling in kidney disease

TWEAK/Fn14 and non-canonical NF-kappaB signaling in kidney disease

The incidence of acute kidney injury (AKI) and chronic kidney disease (CKD) is increasing. However, there is no effective therapy for AKI and current approaches only slow down, but do not prevent progression of CKD. TWEAK is a TNF superfamily cytokine. A solid base of preclinical data suggests a rol...

Full description

Bibliographic Details
Main Authors: Jonay ePoveda, Luis C Tabara, Beatriz eFernandez-Fernandez, Catalina eMartin-Cleary, Ana B Sanz, Rafael eSelgas, Alberto eOrtiz, Maria D Sanchez-Niño
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Acute Kidney Injury
Fibrosis
Inflammation
Kidney
Lupus Nephritis
podocyte
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00447/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00447/full

Similar Items