miR-132-3p priming enhances the effects of mesenchymal stromal cell-derived exosomes on ameliorating brain ischemic injury

miR-132-3p priming enhances the effects of mesenchymal stromal cell-derived exosomes on ameliorating brain ischemic injury

Abstract Backgrounds/aims Mesenchymal stromal cell-derived exosomes (MSC-EXs) could exert protective effects on recipient cells by transferring the contained microRNAs (miRs), and miR-132-3p is one of angiogenic miRs. However, whether the combination of MSC-EXs and miR-132-3p has better effects in i...

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Bibliographic Details
Main Authors: Qunwen Pan, Xiaoli Kuang, Shuyun Cai, Xiang Wang, Donghui Du, Jinju Wang, Yan Wang, Yanyu Chen, Ji Bihl, Yanfang Chen, Bin Zhao, Xiaotang Ma
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Exosome
miR-132-3p
Ischemia and reperfusion
Apoptosis
ROS production
Online Access:http://link.springer.com/article/10.1186/s13287-020-01761-0

Internet

http://link.springer.com/article/10.1186/s13287-020-01761-0

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