Expression and Activity of the BioH Esterase of Biotin Synthesis is Independent of Genome Context

Abstract BioH is an α/β-hydrolase required for synthesis of the pimelate moiety of biotin in diverse bacteria. The bioH gene is found in different genomic contexts. In some cases (e.g., Escherichia coli) the gene is not located within a biotin synthetic operon and its transcription is not coregulate...

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Bibliographic Details
Main Authors: Xinyun Cao, Lei Zhu, Zhe Hu, John E. Cronan
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01490-0