Short Hairpin RNA-Mediated Fibronectin Knockdown Delays Tumor Growth in a Mouse Glioma Model

Glioblastoma multiforme is the most common and lethal primary brain tumor. Glioma progression depends on the rapid proliferation of tumor cells accompanied by an acute immunosuppressive environment, facilitated mainly by tumor infiltration of regulatory T cells (Tregs). In this study, we characteriz...

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Bibliographic Details
Main Authors: Sadhak Sengupta, Suvobroto Nandi, Enal S. Hindi, Derek A. Wainwright, Yu Han, Maciej S. Lesniak
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861080051X