Enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples with rG4-seq 2.0

Enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples with rG4-seq 2.0

Abstract Background RNA G-quadruplexes (rG4s) are non-canonical structural motifs that have diverse functional and regulatory roles, for instance in transcription termination, alternative splicing, mRNA localization and stabilization, and translational process. We recently developed the RNA G-quadru...

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Bibliographic Details
Main Authors: Jieyu Zhao, Eugene Yui-Ching Chow, Pui Yan Yeung, Qiangfeng Cliff Zhang, Ting-Fung Chan, Chun Kit Kwok
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Biology
Subjects:
rG4-seq 2.0
G-quadruplex
Transcriptome
dU adapter cleavage
cDNA library preparation
Online Access:https://doi.org/10.1186/s12915-022-01448-3

Internet

https://doi.org/10.1186/s12915-022-01448-3

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