Preparation and preliminary biological evaluation of Gluc-Lys([Al18F]NOTA)-KE108

Preparation and preliminary biological evaluation of Gluc-Lys([Al18F]NOTA)-KE108

BackgroundRadionuclide labeled somatostatin analogs can specifically bind to somatostatin receptors (SSTRs) on the cell surface of neuroendocrine tumors (NETs), hence be used for imaging or treatment of NETs.PurposeThis study aims to label glycosylated KE108 protein with 18F nuclide, and to investig...

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Bibliographic Details
Main Authors: GAO Fei, DONG Ruilin, SONG Zhihao, ZHANG Yunhan, CHEN Mengyi, QIU Shanshan, WANG Chenglong, XU Lin, CHENG Weihua
Format: Article
Language:zho
Published: Science Press 2021-08-01
Series:He jishu
Subjects:
somatostatin receptor (sstr)
complex aluminum fluoride
neuroendocrine tumors (nets)
ke108 peptides
Online Access:https://www.hjs.sinap.ac.cn/thesisDetails#10.11889/j.0253-3219.2021.hjs.44.080301&lang=zh

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https://www.hjs.sinap.ac.cn/thesisDetails#10.11889/j.0253-3219.2021.hjs.44.080301&lang=zh

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