Toxicity associated with PD-1 blockade after allogeneic haematopoietic cell transplantation

Toxicity associated with PD-1 blockade after allogeneic haematopoietic cell transplantation

Cancer immunotherapy with immune checkpoint inhibitors (ICIs) such as programmed death ligand-1 (PD-L1) blockers offers pronounced clinical benefit with durable responses and a manageable safety profile. Patients with a high risk of immune-related adverse events are generally excluded from clinica...

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Bibliographic Details
Main Authors: Guacimara Ortega Sanchez, Frank Stenner, Stefan Dirnhofer, Jakob Passweg, Sabine Gerull, Jörg P. Halter, Alfred Zippelius, Heinz Läubli
Format: Article
Language:English
Published: SMW supporting association (Trägerverein Swiss Medical Weekly SMW) 2019-11-01
Series:Swiss Medical Weekly
Subjects:
CTLA-4
graft-versus-host disease (GvHD)
immune-related adverse event (irAE)
Immunotherapy
PD-1
Online Access:https://www.smw.ch/index.php/smw/article/view/2692

Internet

https://www.smw.ch/index.php/smw/article/view/2692

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