Characterization and biological evaluation of some novel pyrazolo[3',4':4,5]thieno[2,3-d]pyrimidin-8-ones synthesized via the Gewald reaction

Characterization and biological evaluation of some novel pyrazolo[3',4':4,5]thieno[2,3-d]pyrimidin-8-ones synthesized via the Gewald reaction

The synthesis of substituted pyrazolo[3',4':4,5]thieno[2,3-d]pyrimidin-8-ones (IIIa-j) from 5-amino-3-methyl-1H-thieno[3,2-c]pyrazole-6-carbonitrile (II) is described. The key compound II was synthesized from (5-methyl- -2,4-dihydro-3H-pyrazol-3-ylidene)malononitrile I via the Gewald react...

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Bibliographic Details
Main Authors: Dodiya Dipti K., Trivedi Amit R., Jarsania Samir H., Vaghasia Shailesh J., Shah Viresh H.
Format: Article
Language:English
Published: Serbian Chemical Society 2008-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
pyrazolo[3',4':4,5]thieno[2,3-d]pyrimidin-8-ones
carbonitrile
gewald reaction
antimicrobial activity
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2008/0352-51390807683D.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2008/0352-51390807683D.pdf

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