Development of an enhanced bovine viral diarrhea virus subunit vaccine based on E2 glycoprotein fused to a single chain antibody which targets to antigen-presenting cells

Development of an enhanced bovine viral diarrhea virus subunit vaccine based on E2 glycoprotein fused to a single chain antibody which targets to antigen-presenting cells

Bovine viral diarrhea virus (BVDV) is an important cause of economic losses worldwide. E2 is an immunodominant protein and a promising candidate to develop subunit vaccines. To improve its immunogenicity, a truncated E2 (tE2) was fused to a single chain antibody named APCH, which targets to antigen-...

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Bibliographic Details
Main Authors: Andrea Pecora, Darío A Malacari, María S Pérez Aguirreburualde, Demian Bellido, José M Escribano, María J. Dus Santos, Andrés Wigdorovitz
Format: Article
Language:English
Published: Elsevier España 2015-03-01
Series:Revista Argentina de Microbiología
Subjects:
Glucoproteína E2
Anticuerpo de cadena simple
Vacuna a subunidad
Baculovirus
Virus de la diarrea viral bovina
Online Access:http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-75412015000100002&lng=en&tlng=en

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http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-75412015000100002&lng=en&tlng=en

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