Effect of apigenin on tryptophan metabolic key enzymes expression in lipopolysaccharide-induced microglial cells and its mechanism

Effect of apigenin on tryptophan metabolic key enzymes expression in lipopolysaccharide-induced microglial cells and its mechanism

[Aims] Flavonoid apigenin (API) has a wide range of biological functions, particularly anti-inflammation. Indoleamine 2,3-dioxygenase (IDO) and 2-Amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD) are important tryptophan metabolic enzymes that play pivotal roles in the production of toxic...

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Bibliographic Details
Main Authors: Dian Kurniati, Shizuka Hirai, Yukari Egashira
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Heliyon
Subjects:
Apigenin
ACMSD
IDO
Microglial cells
Neuroinflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022040312

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http://www.sciencedirect.com/science/article/pii/S2405844022040312

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