A semiconductor 96-microplate platform for electrical-imaging based high-throughput phenotypic screening

Abstract High-content imaging for compound and genetic profiling is popular for drug discovery but limited to endpoint images of fixed cells. Conversely, electronic-based devices offer label-free, live cell functional information but suffer from limited spatial resolution or throughput. Here, we int...

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Bibliographic Details
Main Authors: Shalaka Chitale, Wenxuan Wu, Avik Mukherjee, Herbert Lannon, Pooja Suresh, Ishan Nag, Christina M. Ambrosi, Rona S. Gertner, Hendrick Melo, Brendan Powers, Hollin Wilkins, Henry Hinton, Michael Cheah, Zachariah G. Boynton, Alexander Alexeyev, Duane Sword, Markus Basan, Hongkun Park, Donhee Ham, Jeffrey Abbott
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43333-9