Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies

Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies

Background: Vitamin A (VitA), via its active metabolite retinoic acid (RA), is critical for the maintenance of memory function with advancing age. Although its role in Alzheimer's disease (AD) is not well understood, data suggest that impaired brain VitA signaling is associated with the accumul...

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Bibliographic Details
Main Authors: Essi F. Biyong, Cyntia Tremblay, Manon Leclerc, Vicky Caron, Serge Alfos, Jean-Christophe Helbling, Léa Rodriguez, Vincent Pernet, David A. Bennett, Véronique Pallet, Frédéric Calon
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Vitamin A
Aging
Amyloid
Prevention
Diet
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121002916

Internet

http://www.sciencedirect.com/science/article/pii/S0969996121002916

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