Polygenic risk for autism spectrum disorder associates with anger recognition in a neurodevelopment-focused phenome-wide scan of unaffected youths from a population-based cohort.

The polygenic nature and the contribution of common genetic variation to autism spectrum disorder (ASD) allude to a high degree of pleiotropy between ASD and other psychiatric and behavioral traits. In a pleiotropic system, a single genetic variant contributes small effects to several phenotypes or...

Full description

Bibliographic Details
Main Authors: Frank R Wendt, Carolina Muniz Carvalho, Gita A Pathak, Joel Gelernter, Renato Polimanti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009036