Recombinant HcGAPDH Protein Expressed on Probiotic <italic toggle="yes">Bacillus subtilis</italic> Spores Protects Sheep from <italic toggle="yes">Haemonchus contortus</italic> Infection by Inducing both Humoral and Cell-Mediated Responses

Recombinant HcGAPDH Protein Expressed on Probiotic <italic toggle="yes">Bacillus subtilis</italic> Spores Protects Sheep from <italic toggle="yes">Haemonchus contortus</italic> Infection by Inducing both Humoral and Cell-Mediated Responses

ABSTRACT Probiotic Bacillales are effective in controlling pathogens. Live probiotic bacteria improve the composition of the gastrointestinal microbiota, leading to a reduction in pathogen colonization. However, it remains largely unknown how probiotics regulate the host’s immunologic responses and...

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Bibliographic Details
Main Authors: Yi Yang, Guiheng Zhang, Jie Wu, Xueqiu Chen, Danni Tong, Yimin Yang, Hengzhi Shi, Chaoqun Yao, Lenan Zhuang, Jianbin Wang, Aifang Du
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mSystems
Subjects:
Bacillus subtilis
Haemonchus contortus
spore coat
microbiota
recombinant live vaccine
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00239-20

Internet

https://journals.asm.org/doi/10.1128/mSystems.00239-20

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