Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma.
Tuberculosis (TB) granulomas are organized collections of immune cells comprised of macrophages, lymphocytes and other cells that form in the lung as a result of immune response to Mycobacterium tuberculosis (Mtb) infection. Formation and maintenance of granulomas are essential for control of Mtb in...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-05-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2865521?pdf=render |