Mapping the immune landscape in small cell lung cancer by analysing expression of immuno-modulators in tissue biopsies and paired blood samples

Mapping the immune landscape in small cell lung cancer by analysing expression of immuno-modulators in tissue biopsies and paired blood samples

Abstract Small cell lung carcinomas (SCLC) are aggressive tumors with high propensity to metastasize. Recent NCCN guidelines have incorporated immunotherapy in extensive stage SCLC. Limited benefit in few patients compounded by side effects of unwonted immune-checkpoint-inhibitor (ICPI) usage necess...

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Bibliographic Details
Main Authors: Rimlee Dutta, Amber Rathor, Hanuman Prasad Sharma, Hem Chandra Pandey, Prabhat Singh Malik, Anant Mohan, Aruna Nambirajan, Rajeev Kumar, Deepali Jain
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30841-3

Internet

https://doi.org/10.1038/s41598-023-30841-3

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