Hypoxic preconditioned MSCs-derived small extracellular vesicles for photoreceptor protection in retinal degeneration

Hypoxic preconditioned MSCs-derived small extracellular vesicles for photoreceptor protection in retinal degeneration

Abstract Photoreceptor apoptosis is an important pathogenesis of retinal degeneration and a primary cause of vision loss with limited treatment methods. Mesenchymal stem/stromal cells-derived small extracellular vesicles (MSC-sEVs) have shown therapeutic value in various ocular disorders. Recent stu...

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Bibliographic Details
Main Authors: Yuntong Sun, Yuntao Sun, Shenyuan Chen, Yifan Yu, Yongjun Ma, Fengtian Sun
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Photoreceptor apoptosis
Retinal degeneration
Small extracellular vesicles
Mesenchymal stem/stromal cells
Hypoxia
GAP43
Online Access:https://doi.org/10.1186/s12951-023-02225-2

Internet

https://doi.org/10.1186/s12951-023-02225-2

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