Expansion of cancer germline antigen–specific cytotoxic T lymphocytes for immunotherapy

The cancer germline antigens MAGE-A1, MAGE-A3, and NY-ESO-1 can be used to target relapsed or therapy-resistant malignant solid tumors, and previous studies have demonstrated that these antigens can be epigenetically upregulated on the surface of tumor cells following exposure to low-dose demethylat...

Description complète

Détails bibliographiques
Auteurs principaux: Deepa Kolaseri Krishnadas, Yali Wang, Kumaran Sundaram, Fanqi Bai, Kenneth G Lucas
Format: Article
Langue:English
Publié: IOS Press 2017-07-01
Collection:Tumor Biology
Accès en ligne:https://doi.org/10.1177/1010428317701309