Phenotypic bistability in Escherichia coli's central carbon metabolism

Abstract Fluctuations in intracellular molecule abundance can lead to distinct, coexisting phenotypes in isogenic populations. Although metabolism continuously adapts to unpredictable environmental changes, and although bistability was found in certain substrate‐uptake pathways, central carbon metab...

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Bibliographic Details
Main Authors: Oliver Kotte, Benjamin Volkmer, Jakub L Radzikowski, Matthias Heinemann
Format: Article
Language:English
Published: Springer Nature 2014-07-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20135022