Germline Mutations in Patients With Early-Onset Prostate Cancer

Germline Mutations in Patients With Early-Onset Prostate Cancer

ObjectiveTo investigate the inherited mutations and their association with clinical features and treatment response in young-onset prostate cancer patients.MethodTargeted gene sequencing on 139 tumor susceptibility genes was conducted with a total of 24 patients diagnosed with PCa under the age of 6...

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Bibliographic Details
Main Authors: Tang Tang, Xintao Tan, Ze Wang, Shuo Wang, Yapeng Wang, Jing Xu, Xiajie Wei, Dianzheng Zhang, Qiuli Liu, Jun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
early-onset
next-generation sequencing
germline mutations
homologous recombination associated genes
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.826778/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.826778/full

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