Resistance to Immune Checkpoint Inhibitors Secondary to Myeloid-Derived Suppressor Cells: A New Therapeutic Targeting of Haematological Malignancies

Resistance to Immune Checkpoint Inhibitors Secondary to Myeloid-Derived Suppressor Cells: A New Therapeutic Targeting of Haematological Malignancies

Myeloid-derived suppressor cells (MDSCs) are a set of immature myeloid lineage cells that include macrophages, granulocytes, and dendritic cell precursors. This subpopulation has been described in relation to the tumour processes at different levels, including resistance to immunotherapy, such as im...

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Bibliographic Details
Main Authors: Alejandro Olivares-Hernández, Luis Figuero-Pérez, Eduardo Terán-Brage, Álvaro López-Gutiérrez, Álvaro Tamayo Velasco, Rogelio González Sarmiento, Juan Jesús Cruz-Hernández, José Pablo Miramontes-González
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Clinical Medicine
Subjects:
myeloid-derived suppressor cells (MDSCs)
immune checkpoint inhibitors (ICIs)
haematological malignancies
immune resistance
Online Access:https://www.mdpi.com/2077-0383/10/9/1919

Internet

https://www.mdpi.com/2077-0383/10/9/1919

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