Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1
Chromosome specific retention of cancer associated DNA hypermethylation following pharmacological inhibition of DNMT1 is shown, with residual CpG methylation on the X chromosome compared to autosomes, suggesting a separate mechanism of methylation.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-06-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03509-3 |