Using magnetic mesoporous silica nanoparticles armed with EpCAM aptamer as an efficient platform for specific delivery of 5-fluorouracil to colorectal cancer cells

Using magnetic mesoporous silica nanoparticles armed with EpCAM aptamer as an efficient platform for specific delivery of 5-fluorouracil to colorectal cancer cells

Background: Theranostic nanoparticles with both imaging and therapeutic capacities are highly promising in successful diagnosis and treatment of advanced cancers.Methods: Here, we developed magnetic mesoporous silica nanoparticles (MSNs) loaded with 5-fluorouracil (5-FU) and surface-decorated with p...

Full description

Bibliographic Details
Main Authors: Aseel Kamil Mohammad Al-Mosawi, Ahmad Reza Bahrami, Sirous Nekooei, Amir Sh. Saljooghi, Maryam M. Matin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
colorectal cancer
mesoporous silica nanoparticles
superparamagnetic iron oxide
5-fluorouracil
epithelial cell adhesion molecule
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1095837/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1095837/full

Similar Items