Effect of Ras Inhibition in Hematopoiesis and BCR/ABL Leukemogenesis

<p>Abstract</p> <p>Ras small GTPases are activated in many hematopoietic growth factor signaling and in hematological malignancies, but their role in hematopoiesis and leukemogenesis is not completely known. Here we examined the effect of Ras inhibition by a dominant negative mutan...

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Bibliographic Details
Main Authors: Baum Karina J, Ren Ruibao
Format: Article
Language:English
Published: BMC 2008-06-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/1/1/5