JNK signaling mediates acute rejection via activating autophagy of CD8+ T cells after liver transplantation in rats

JNK signaling mediates acute rejection via activating autophagy of CD8+ T cells after liver transplantation in rats

BackgroundAcute rejection (AR) after liver transplantation (LT) remains an important factor affecting the prognosis of patients. CD8+ T cells are considered to be important regulatory T lymphocytes involved in AR after LT. Our previous study confirmed that autophagy mediated AR by promoting activati...

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Bibliographic Details
Main Authors: Xiaowen Wang, Wenfeng Zhu, Haoqi Chen, Xuejiao Li, Wenjie Zheng, Yuan Zhang, Ning Fan, Xiaolong Chen, Genshu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
JNK signaling
autophagy
CD8+ T cells
acute rejection
liver transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359859/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359859/full

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