The Effect of Apolipoprotein E ε4 (APOE ε4) on Visuospatial Working Memory in Healthy Elderly and Amnestic Mild Cognitive Impairment Patients: An Event-Related Potentials Study

The Effect of Apolipoprotein E ε4 (APOE ε4) on Visuospatial Working Memory in Healthy Elderly and Amnestic Mild Cognitive Impairment Patients: An Event-Related Potentials Study

Background: Apolipoprotein E (APOE) ε4 is the only established risk gene for late-onset, sporadic Alzheimer’s disease (AD). Previous studies have provided inconsistent evidence for the effect of APOE ε4 status on the visuospatial working memory (VSWM).Objective: The aim was to investigate the effect...

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Bibliographic Details
Main Authors: Li-Hua Gu, Jiu Chen, Li-Juan Gao, Hao Shu, Zan Wang, Duan Liu, Yan-Na Yan, Shi-Jiang Li, Zhi-Jun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
apolipoprotein E
event-related potential
amnestic mild cognitive impairment
visuospatial working memory
P300
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00145/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00145/full

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