Sildenafil for treating patients with COVID-19 and perfusion mismatch: a pilot randomized trial

Sildenafil for treating patients with COVID-19 and perfusion mismatch: a pilot randomized trial

Abstract Background SARS-CoV-2 seems to affect the regulation of pulmonary perfusion. Hypoperfusion in areas of well-aerated lung parenchyma results in a ventilation–perfusion mismatch that can be characterized using subtraction computed tomography angiography (sCTA). This study aims to evaluate the...

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Bibliographic Details
Main Authors: Mario G. Santamarina, Ignacio Beddings, Felipe Martinez Lomakin, Dominique Boisier Riscal, Mónica Gutiérrez Claveria, Jaime Vidal Marambio, Nicole Retamal Báez, Cristian Pavez Novoa, César Reyes Allende, Paulina Ferreira Perey, Miguel Gutiérrez Torres, Camila Villalobos Mazza, Constanza Vergara Sagredo, Sebastian Ahumada Bermejo, Eduardo Labarca Mellado, Elizabeth Barthel Munchmeyer, Solange Marchant Ramos, Mariano Volpacchio, Jorge Vega
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Critical Care
Subjects:
COVID-19
Sildenafil
Subtraction CT angiography
Ventilation–perfusion ratio
Blood gas analysis
Mechanical ventilation
Online Access:https://doi.org/10.1186/s13054-021-03885-y

Internet

https://doi.org/10.1186/s13054-021-03885-y

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