The dose regimen formulation of doxycycline hydrochloride and florfenicol injection based on ex vivo pharmacokinetic-pharmacodynamic modeling against the Actinobacillus pleuropneumoniae in pigs

The dose regimen formulation of doxycycline hydrochloride and florfenicol injection based on ex vivo pharmacokinetic-pharmacodynamic modeling against the Actinobacillus pleuropneumoniae in pigs

Abstract Doxycycline hydrochloride and florfenicol combination (DoxHcl&FF) is an effective treatment for respiratory diseases. In the study, our objective was to evaluate the activity of DoxHcl&FF against Actinobacillus pleuropneumoniae (APP) in porcine pulmonary epithelial lining fluid (PEL...

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Bibliographic Details
Main Authors: Yuanyuan Yuan, Boyu An, Shuyu Xie, Wei Qu, Haihong Hao, Lingli Huang, Wanhe Luo, Jixiang Liang, Dapeng Peng
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Animal Diseases
Subjects:
Florfenicol
Doxycycline hydrochloride
PK-PD
Pig
Dose regimen
Actinobacillus pleuropneumoniae
Online Access:https://doi.org/10.1186/s44149-023-00066-y

Internet

https://doi.org/10.1186/s44149-023-00066-y

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