AMP-Activated Protein Kinase α1 Regulates Cardiac Gap Junction Protein Connexin 43 and Electrical Remodeling Following Pressure Overload

AMP-Activated Protein Kinase α1 Regulates Cardiac Gap Junction Protein Connexin 43 and Electrical Remodeling Following Pressure Overload

Background/Aims: Adenosine 5'-monophosphate (AMP)-activated protein kinase (Ampk) modulates a wide array of cellular functions and regulates various ion channels and transporters. In failing human hearts an increased Ampkα1 activity was observed. The present study aimed to uncover the impact of...

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Bibliographic Details
Main Authors: Ioana Alesutan, Jakob Voelkl, Florian Stöckigt, Sobuj Mia, Martina Feger, Uwe Primessnig, Mentor Sopjani, Carlos Munoz, Oliver Borst, Meinrad Gawaz, Burkert Pieske, Bernhard Metzler, Frank Heinzel, Jan Wilko Schrickel, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Electrical remodeling
Conduction
Ampkα1
Cx43
Ubiquitination
Online Access:http://www.karger.com/Article/FullText/369706

Internet

http://www.karger.com/Article/FullText/369706

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