Synergistic effects of polymyxin and vancomycin combinations on carbapenem- and polymyxin-resistant Klebsiella pneumoniae and their molecular characteristics

Synergistic effects of polymyxin and vancomycin combinations on carbapenem- and polymyxin-resistant Klebsiella pneumoniae and their molecular characteristics

ABSTRACT The emergence and spread of polymyxin resistance, especially among Klebsiella pneumoniae isolates, threaten the effective management of infections. This study profiled for polymyxin resistance mechanisms and investigated the activity of polymyxins plus vancomycin against carbapenem- and pol...

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Bibliographic Details
Main Authors: Ozioma Forstinus Nwabor, Arnon Chukamnerd, Pawarisa Terbtothakun, Lois Chinwe Nwabor, Komwit Surachat, Sittiruk Roytrakul, Supayang Piyawan Voravuthikunchai, Sarunyou Chusri
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
polymyxins
vancomycin
combination therapy
population analysis profiling
genomic profiling
protein profiling
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01199-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01199-23

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