Elevated Risk of Fluoropyrimidine-Associated Toxicity in European Patients with <i>DPYD</i> Genetic Polymorphism: A Systematic Review and Meta-Analysis
<b>Background:</b> Fluoropyrimidine is widely used owing to its clinical efficacy, however, patients with dihydropyrimidine dehydrogenase (DPD) deficiency can experience fluoropyrimidine-associated toxicity. The dihydropyrimidine dehydrogenase (<i>DPYD</i>) gene encodes DPD,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-02-01
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| Series: | Journal of Personalized Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4426/12/2/225 |