COMMON METHODS INCREASING THE SOLUBILITY OF POORLY SOLUBLE HYDROPHOBIC SUBSTANCES

COMMON METHODS INCREASING THE SOLUBILITY OF POORLY SOLUBLE HYDROPHOBIC SUBSTANCES

There are several methods for solving the problem of an adequate dosage form for the hydrophobic and poorly soluble pharmaceutical substances which comprise a structure modification, preparation of solid dispersion systems, a change in pH, the use of cosolvents and solubilizers introduction of subst...

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Bibliographic Details
Main Authors: I. D. Gulyakin, L. L. Nikolaeva, N. A. Oborotova, M. V. Dmitrieva, A. V. Lantsova, E. V. Sanarova, O. L. Orlova, A. P. Polozkova, H. I. Lavrukhin, N. D. Bunyatyan
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
сорастворители
солюбилизаторы
твердые дисперсные системы
комплексообразование
наносистемы
Online Access:https://www.pharmjournal.ru/jour/article/view/83

Internet

https://www.pharmjournal.ru/jour/article/view/83

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