Alternative buffer systems in biopharmaceutical formulations and their effect on protein stability

The formulation of biopharmaceutical drugs is designed to eliminate chemical instabilities, increase conformational and colloidal stability of proteins, and optimize interfacial stability. Among the various excipients involved, buffer composition plays a pivotal role. However, conventional buffers l...

Полное описание

Библиографические подробности
Главные авторы: Lebar Blaž, Zidar Mitja, Mravljak Janez, Šink Roman, Žula Aleš, Pajk Stane
Формат: Статья
Язык:English
Опубликовано: Sciendo 2024-09-01
Серии:Acta Pharmaceutica
Предметы:
Online-ссылка:https://doi.org/10.2478/acph-2024-0022