Sirtuins and cognition: implications for learning and memory in neurological disorders

Sirtuins are an evolutionarily conserved family of regulatory proteins that function in an NAD+ -dependent manner. The mammalian family of sirtuins is composed of seven histone deacetylase and ADP-ribosyltransferase proteins (SIRT1-SIRT7) that are found throughout the different cellular compartments...

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Bibliographic Details
Main Authors: Eric Fagerli, Iris Escobar, Fernando J. Ferrier, Charles W. Jackson, Efrain J. Perez-Lao, Miguel A. Perez-Pinzon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.908689/full