In vitro culture of murine megakaryocytes from fetal liver-derived hematopoietic stem cells

Megakaryocytes (MKs) are specialized precursor cells committed to producing and proliferating platelets. In a cytoskeletal-driven process, mature MKs generate platelets by releasing thin cytoplasmic extensions, named proplatelets, into the sinusoids. Due to knowledge gaps in this process and mountin...

Full description

Bibliographic Details
Main Authors: Prakrith Vijey, Benjamin Posorske, Kellie R Machlus
Format: Article
Language:English
Published: Taylor & Francis Group 2018-08-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2018.1492107