Optimized protocol for quantification of extracellular nicotinamide adenine dinucleotide: evaluating clinical parameters and pre-analytical factors for translational research

Optimized protocol for quantification of extracellular nicotinamide adenine dinucleotide: evaluating clinical parameters and pre-analytical factors for translational research

Nicotinamide adenine dinucleotide (NAD+), a coenzyme for more than 500 enzymes, plays a central role in energy production, metabolism, cellular signaling, and DNA repair. Until recently, NAD+ was primarily considered to be an intracellular molecule (iNAD+), however, its extracellular species (eNAD+)...

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Bibliographic Details
Main Authors: Al-Hussein Ahmed Saqr, Can Kamali, Philipp Brunnbauer, Nils Haep, Pia Koch, Karl-Herbert Hillebrandt, Eriselda Keshi, Simon Moosburner, Raphael Mohr, Nathanael Raschzok, Johann Pratschke, Felix Krenzien
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Medicine
Subjects:
extracellular
nicotinamide adenine dinucleotide (NAD+)
quantification
plasma
enzymatic assay
intracellular
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1278641/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1278641/full

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