Variations in the interaction of human defensins with Escherichia coli: Possible implications in bacterial killing.

Human α and β-defensins are cationic antimicrobial peptides characterized by three disulfide bonds with a triple stranded β-sheet motif. It is presumed that interaction with the bacterial cell surface and membrane permeabilization by defensins is an important step in the killing process. In this stu...

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Bibliographic Details
Main Authors: Basil Mathew, Ramakrishnan Nagaraj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5397029?pdf=render